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Search Term: " glucose metabolism "
Understanding Benfotiamine: The Fat-Soluble, Bioavailable and Physiologically Active Form of Thiamine   
Date:
July 27, 2023 12:12 PM
What if there existed a form of thiamine that was more bioavailable and physiologically active than the conventional form we all know about? Well, that form does exist, and it is called Benfotiamine. Benfotiamine has been gaining popularity lately, especially among people dealing with diabetes and other metabolic disorders. But what exactly is Benfotiamine, and what makes it different? Lets explore Benfotiamine, its bioavailability, and its physiological effects. Thiamine, also known as Vitamin B1, is a nutrient that plays a crucial role in energy production, nerve function, and metabolism. It is a water-soluble vitamin, which means it dissolves in water and is not stored by the body. However, conventional forms of thiamine have a limited ability to cross cell membranes and are easily excreted out of the body, rendering it ineffective for some individuals. This is where Benfotiamine comes in; it is a modified form of Vitamin B1 that is fat-soluble, highly bioavailable, and because cells are wrapped in lipid fat this form of B1 is capable of crossing cell membranes with ease. Since our cell membranes are composed of lipids, fat-soluble nutrients can easily penetrate the cell barrier and get into living cells where the vitamin is needed. Upon entering the bloodstream, benfotiamine is converted to thiamin pyrophosphate (TPP), the biologically active co-enzyme of thiamin, which is responsible for energy metabolism. By raising the blood levels of TPP, benfotiamine has been shown to support glucose metabolism, reduce oxidative stress and inflammation, and protect against the damage caused by high levels of advanced glycation end products (AGEs). In addition to its bioavailability, benfotiamine has been shown to have several physiological effect on the body. One of the key enzymes that benfotiamine influences is transketolase, which is involved in the pentose phosphate pathway, a metabolic pathway that generates NADPH, a vital molecule that protects cells against oxidative stress. By stimulating transketolase, benfotiamine supports the diversion of excess glucose to the pentose phosphate pathway, thereby reducing the production of reactive oxygen species and increasing the production of NADPH. Another significant benefit of benfotiamine is that it helps protect the nervous system. Chronic high blood glucose levels are known to cause oxidative stress and to damage the peripheral and central nervous systems. However, benfotiamine has been shown to help lower oxidative stress markers and reduce the risk of nerve damage. This can in turn help reduce pain, numbness, and tingling sensations associated with nerve damage, making it a promising adjunct therapy for people with diabetic neuropathy. In Summary: benfotiamine is a modified and bioavailable form of thiamine that offers unique benefits compared to conventional forms of Vitamin B1. Its fat-solubility enables it to cross cell membranes, raise levels of thiamin pyrophosphate, stimulate the transketolase enzyme, and support proper glucose metabolism. Its notable effects on the nervous system make it an attractive therapeutic agent for people with diabetic neuropathy. If you're seeking an alternative and highly effective form of thiamine, benfotiamine is definitely worth considering. Give it a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6580) Magnesium Oxide Supports Energy Production and Metabolism 
Date:
November 02, 2022 03:01 PM
Magnesium is a mineral that is critical for energy production, muscle contraction, nerve impulse transmission, and bone mineralization. It is a required cofactor for an estimated 300 enzymes. Among the reactions catalyzed by these enzymes are fatty acid synthesis, protein synthesis, and glucose metabolism. Magnesium status is also important for regulation of calcium balance through its effects on the parathyroid gland. Magnesium oxide is a popular supplement because it is easily absorbed and bioavailable.* It features magnesium in its purest form and provides support for energy production.* In addition, magnesium oxide is essential for enzyme function* and helps to maintain healthy bones.* What are the benefits of magnesium oxide? Magnesium oxide is easily absorbed and bioavailable. This makes it an ideal supplement for those who want to increase their magnesium intake.* It features magnesium in its purest form and provides support for energy production.* In addition, magnesium oxide is essential for enzyme function* and helps to maintain healthy bones.* How does magnesium oxide work? Magnesium oxide works by providing your body with magnesium in a highly bioavailable form. This means that your body can easily absorb and use the magnesium for various functions.* Among these functions are energy production, protein synthesis, and regulation of calcium levels in the blood.* Who should take magnesium oxide? Anyone who wants to increase their magnesium intake can benefit from taking magnesium oxide. This includes people who are interested in supporting their energy levels*, maintaining healthy bones*, or ensuring proper enzyme function*. Talk to your healthcare provider if you have any questions about whether magnesium oxide is right for you. Magnesium oxide is a popular supplement because it is easily absorbed and bioavailable. It features magnesium in its purest form and provides support for energy production. In addition, magnesium oxide is essential for enzyme function and helps to maintain healthy bones. [*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.]
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6553) Do You Know How Important Magnesium Is For The Body?
Date:
October 31, 2022 05:02 PM
You may not have realized it, but magnesium is an essential mineral for your body. It aids in energy production and metabolism, muscle contraction, nerve impulse transmission, and bone mineralization. Magnesium is also a required cofactor for an estimated 300 enzymes. That means it helps catalyze reactions like fatty acid synthesis, protein synthesis, and glucose metabolism. Not to mention, magnesium status is also important for regulation of calcium balance through its effects on the parathyroid gland. Whew! As you can see, this mineral is pretty important stuff. Read on to learn more about why magnesium is so critical for our health. Magnesium and Energy Production One of the most important functions of magnesium is that it helps us produce energy. Every single cell in our bodies need energy to function properly, and magnesium plays a key role in the process of converting the food we eat into that much-needed energy. For example, magnesium is involved in breaking down carbohydrates into glucose which can then be used for energy by the cells. Magnesium and Muscle Functioning In addition to helping produce energy, magnesium is also necessary for proper muscle functioning. This mineral helps muscles relax after they contract as well as regulates electrolyte balance in the body. electrolyte imbalance can lead to muscle cramping, spasms, or even irregular heartbeats, so it's crucial that we maintain healthy levels of magnesium to keep our muscles functioning properly. How to Get More Magnesium Now that you know all of the important functions that magnesium plays in our bodies, you're probably wondering how you can make sure you're getting enough of this essential mineral. The best way to ensure adequate magnesium intake is through diet since our bodies cannot produce this mineral on their own. Some good dietary sources of magnesium include leafy green vegetables, legumes, nuts and seeds, whole grains, dairy products, fish, and meat. You can also get your recommended daily intake of magnesium through supplements if you feel like your diet is lacking or if you have a medical condition that requires extra magnesium (such as diabetes). As you can see, magnesium is an essential mineral with many vital functions in our bodies. from helping produce energy to regulating electrolyte balance, this nutrient plays a big role in keeping us healthy and function properly both physically and mentally. Make sure you are getting enough magnesium in your diet by consuming foods like leafy greens, legumes, whole grains, dairy products ,and nuts or by taking supplements if necessary. Your body will thank you!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6551) Gymnema Sylvestre - An Herb That Promotes Healthy Glucose Metabolism
Date:
October 25, 2022 02:41 PM
Gymnema sylvestre is an herb that has been used traditionally in India for centuries. Modern research has shown that this herb may help to support healthy glucose metabolism through its ability to promote healthy pancreatic function.* In addition, gymnema exhibits potent free-radical scavenging properties.* NOW® Gymnema Sylvestre Extract is standardized to gymnemic acids, which are the compounds that have been identified as its bioactive constituents.* Gymnema sylvestre is a woody climbing shrub that grows in the tropical forests of central and southern India. The leaves of the plant have been used traditionally in Ayurvedic medicine for centuries.1 Modern science has validated many of the traditional uses for this herb and has identified several key active components.2-4 Promotes Healthy Pancreatic Function* One of the traditional uses for Gymnema sylvestre was to support healthy glucose metabolism.5 This effect was thought to be due to the herb’s ability to promote healthy pancreatic function.* The primary active components in Gymnema sylvestre – gymnemic acids – have been shown in animal studies to increase insulin secretion from the pancreas.6,7 In addition, these compounds appear to help maintain healthy beta cell function and architecture.8,9 Maintenance of normal beta cell function is critical for long-term metabolic health since these cells are responsible for producing insulin in response to rising blood sugar levels.10,11 Exhibits Potent Free-Radical Scavenging Properties* In addition to supporting healthy pancreatic function, recent research has shown that Gymnema sylvestre extracts also possess potent free-radical scavenging properties.*12 These effects were attributed primarily to the gymnemic acids present in the herb.13 This natural free-radical scavenging activity may help support cellular health.* NOW® Gymnema Sylvestre Extract is standardized to a minimum of 25% gymnemic acids and provides 6:1 extract potency. For easy supplementation, take 2 capsules 1 or 2 times daily with food or water. In Summary: Gymnema sylvestre is an herb with a long history of use in Ayurvedic medicine. Modern science has validated many of the traditional uses for this herb and has identified several key active components, including gymnemic acids which have been shown in animal studies to increase insulin secretion from the pancreas. Additionally, extracts of Gymnema sylvestre have been shown to possess potent free-radical scavenging properties which may help support cellular health.* NOW® Gymnema Sylvestre Extract is standardized to a minimum of 25% gymnemic acids and provides 6:1 extract potency. For easy supplementation, take 2 capsules 1 or 2 times daily with food or water.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6523) The Health Benefits of Berberine
Date:
September 12, 2022 04:22 PM
Berberine is a natural constituent of herbs such as goldenseal, Oregon grape, and barberry. Clinical studies have demonstrated that berberine helps to support already normal glucose and lipid metabolism.* Because berberine is known for its limited bioavailability, this product includes caprate (C10, a medium-chain triglyceride) to promote optimal absorption and maintenance of gastrointestinal comfort during berberine supplementation.* Berberine has a long history of use in Traditional Chinese Medicine and Ayurveda for supporting already normal liver function and healthy digestion.* It is also one of the most well-studied botanicals for already normal glucose metabolism support, with research indicating it may work by activating an AMPK-dependent pathway.* Berberine May Help To Support Normal glucose metabolism* Berberine is a plant alkaloid with a long history of use in Traditional Chinese Medicine for promoting already normal liver function.* extraction process ensures a consistent level of berberine from batch to batch. In addition, this product provides 500 mg of berberine hydrochloride per vegetarian capsule. Several clinical studies have demonstrated that berberine can help to support normal glucose metabolism in already healthy individuals when taken at dosages of 900 mg to 1,500 mg per day.* In a placebo-controlled human clinical trial involving subjects with prediabetes who were given 500 mg of berberine two times daily for 12 weeks, researchers observed improvements in already normal fasting blood sugar, HbA1c, and triglyceride levels (as well as increases in HDL-cholesterol) compared to placebo group.* May Also Help To Support Lipid Metabolism* In addition to its effects on already normal glucose metabolism, berberine has also been shown to help support lipid metabolism in already healthy individuals. In a 12-week, double-blind, placebo-controlled human clinical trial involving subjects with mild elevations in LDL cholesterol who were given 500 mg of berberine two times daily, researchers noted statistically significant decreases in total cholesterol and LDL cholesterol levels (along with increases in HDL cholesterol) compared to placebo group.* Berberine is a potent botanical extract that has been traditionally used for supporting liver function and healthy digestion. Additionally, it is one of the most well studied botanicals for supporting already normal glucose metabolism. Numerous clinical trials show that it can help maintain already normal levels of fasting blood sugar as well as HbA1c and triglycerides. Furthermore, berberine has also been shown to promote already healthy lipid metabolism by supporting already normal levels of total cholesterol, LDL cholesterol, and HDL cholesterol. Therefore, if you are looking for an herbal supplement to support your overall health and well being, berberine is definitely worth considering.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6443) Catechins in green tea found to improve symptoms of metabolicsyndrome in obese people
Date:
April 25, 2019 04:43 PM
Green tea not only tastes good, but it also has very beneficial health factors. Among these factors includes the fact that it contains catechins, which are polyphenols that are a good barrier to diabetes and stress. These catechins can also help with metabolic syndrome, which is a syndrome that causes people to have higher than normal levels of abdominal fat and a slowed down metabolism. This could potentially lead to lowered rates of obesity when consumed by the public. Key Takeaways:
"In this study, the researchers wanted to determine if catechins were beneficial for reducing abdominal fat and improving metabolic syndrome." Read more: https://www.naturalnews.com/2019-02-27-catechins-improve-symptoms-of-metabolic-syndrome-in-obese-people.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6183) Cocoa has profound healing properties, beating even acai andblueberries
Date:
April 02, 2019 02:02 PM
Cocoa is not only delicious, but also has healing properties. Cocoa is rich in antioxidants which are also found in berries, tea and wine. The antioxidants are known to help inflammation and blood pressure levels. Flavanols are also found in cocoa. These are correlated to improved heart function by controlling the levels of nitric oxide in your blood. Cocoa may even help with side effects of Type II Diabetes, brain health and reducing your risk of cancer. Key Takeaways:
"While cocoa does possess anti-diabetic properties, it does not mean that eating more chocolate will provide even more anti-diabetic properties. To a certain extent, the intake of cocoa can improve glucose metabolism and insulin sensitivity." Read more: https://www.naturalnews.com/2019-01-29-cocoa-has-profound-healing-properties.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6109) New research finds astaxanthin may help diabetics by lowering blood pressure and improving glucose metabolism
Date:
April 03, 2018 09:17 AM
Perhaps one of the most widespread and minimally understood illnesses in society today is that of diabetes, especially considering the fact that it impacts so many people, and there has been little headway in identifying a proper cure. However, recent research has provided hope for those who are suffering with the illness, as studies now are finding that astaxanthin may be helpful in lowering blood pressure for those dealing with diabetes, and improving glucose metabolism as well. Key Takeaways:
"Now, a new study shows that scientists are just beginning to scratch the surface when it comes to the potential of astaxanthin." Read more: https://www.naturalnews.com/2018-04-01-astaxanthin-may-help-diabetics-by-lowering-blood-pressure-and-improving-glucose-metabolism.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5570) 5 Heart-Healthy Breakfast Ideas Other Than Oatmeal
Date:
February 19, 2017 07:59 AM
There are five heart healthy breakfast ideas and they do not include oatmeal at all. People who eat breakfast everyday are said to have less of a chance of high cholesterol and high blood pressure. The people who skipped breakfast were found to be obese and have poor health a lot of the time. Wheat berries are one food to eat in the morning. Key Takeaways:
"Oatmeal is a mainstay of most heart-healthy diets." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3973) Each Meal You Eat Triggers An Immune System Response, Sets Off Inflammation
Date:
January 25, 2017 12:59 PM
The research, carried out at the University Hospital Basel, was published, Jan. 16, in the journal Nature Immunology, and addresses the series of reactions taking place in the human body, both for healthy and overweight people. When it comes to people who suffer from diabetes, this substance causes chronic inflammation, thus killing the cells responsible for the production of insulin. IL-1 and insulin increased the uptake of glucose into macrophages, and insulin reinforced a pro-inflammatory pattern via the insulin receptor, glucose metabolism, production of reactive oxygen species, and secretion of IL-1 mediated by the NLRP3 inflammasome, noted the research. Key Takeaways:
"However, this new research presents the positive aspects of this type of inflammation triggered by digestion, as it seems that healthy people only have a short-term inflammatory response, directed at leveling the sugar uptake and the immune system." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3827) Can L-Leucine Help Glucose Metabolism And Insulin Function?
Date:
June 02, 2014 08:54 AM
What is a leucine
What does leucine do L-leucine has direct bearing on the amount of insulin produced. L-leucine will stimulate the amount of insulin produced by the pancreas. One of the ways in which it influences the amount of insulin produced is by enhancing glutaminolysis by allosterically activating GDH (glutamate dehydrogenase). Benefits of leucine Increased insulin levels have a major implications on glucose metabolism. Increased insulin level will directly result into faster glucose absorption into the blood stream. Increased glucose metabolism prevents the body from using lean muscles to supply energy during workouts. Unlike isoleucine and valine, L-leucine are converted to glucose slowly and thus you can have sustained energy for long. It is also very effective in muscle building. By stimulating insulin release and glucose metabolism, it enables key nutrients such as amino acids, Creatine and glucose to enter muscle cells. Since insulin will stimulate rapid muscle synthesis while inhibiting protein breakdown, L-leucine will build lean muscle mass with a short period. L-leucine is alternative to steroids, it is safer and its effects are lasting. During workouts, it supports oxidative metabolism in muscles and decrease protein degradation. If you are looking for the best way you can build muscle mass and strength without adverse effects, L-leucine is premier supplement. Apart from building muscle, l-leucine will also improve brain functions. You can take more workouts. L-leusine supplement has been used by many body builders and has been proved beyond doubt to be effective supplement. If you have been wondering if l-leucine help glucose metabolism and insulin function, no doubt it is can. You can also red more by visiting //www.livestrong.com/article/261185-what-are-the-functions-of-leucine/ //www.ncbi.nlm.nih.gov/pmc/articles/PMC2969169/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3131) Did You Know That Chromium Can Help Cells Absorb Glucose?
Date:
November 03, 2013 12:30 AM
What is Chromium
Chromium is a trace mineral that human body needs in very small amounts for maintenance of health and digestion of food. In nature, chromium of occurs in two isotopes- trivalent (chromium 3+) and hexavalent (chromium 6+). The biologically active isotope is the trivalent isotope and it is found in various food types. The other isotope results from industrial pollution and is very toxic. Chromium has been demonstrated to be an essential trace mineral in glucose handling by the body. It is known to enhance the action of insulin, a hormone that plays a vital role in metabolism and storage of carbohydrates, proteins and fat in the body. The effects of chromium on glucose metabolism were realized in 1957 when it was observed that a compound in brewer’s yeast could prevent age related decline in insulin sensitivity in rats. Studies found that his compound contained chromium. How Does Chromium Work
This trace mineral helps cells absorb glucose. When taken in appropriate amounts, chromium enhances the action of the anabolic hormone insulin in the cells. Usually, insulin is synthesized and stored in the pancreas. Intake of carbohydrates and indeed other food types stimulates the secretion of insulin from the pancreas into blood. Once in the blood it binds to specific receptors on cells, especially muscle and liver. This is where chromium comes in. Chromium is believed to enhance the action of insulin by increasing the sensitivity of the cells to insulin. In other words, it promotes the absorption of glucose into cells. This has many benefits. It prevents the development of glucose intolerance and therefore the onset of type 2 diabetes mellitus. Those people with chromium deficiency may actually develop type 2 diabetes mellitus with its attendant complications. In addition to effects on insulin and glucose metabolism, chromium can also promote lipid metabolism, prevent loss of calcium and promote muscle building.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2873) Why Would You Want A Time Released Chromium Supplement?
Date:
January 03, 2013 04:34 PM
Chromium is an important trace mineral for carbohydrates and fats processing by the human body. With the recent eating habits of refined foods, it's generally naturally deficient to many people. It's recommended to consume at least 50 micrograms of it each day. Similarly, the eating habits of today expose majority of people to diabetes. Chromium plays a major role in helping the body cells respond to insulin. In addition, a sufficient level of the mineral availability to the body leads to lower insulin necessity. On the other hand, its deficiency in the body has been associated with diabetes. It helps prevent diabetes by aiding insulin in glucose metabolism as well as preventing insulin resistance for victims already using insulin shots. It's generally low in the blood but it plays a major role of enhancing insulin efficiency thereby helps control blood sugar levels. Food Sources: You can get chromium from foods like broccoli, green beans, grape juice, potatoes, bananas, beef, orange juice and apples. There are also supplements that come in various forms and strengths. For instance, there are chromium picolinate, chromium chloride, chromium polynicotinate, chromium GTF and many others. These supplements differ in their absorption rates but have been proven in several studies to lower blood sugar as well as cholesterol. Some supplements are also safe to take alongside other medications. However, such a decision should always be taken with the consent of a medical doctor. Victims of type 2 diabetes have usually been found to have low levels of chromium in their bodies. Due to this reason, supplements have greatly assisted such individuals tackle diabetes. Similarly, women suffering from gestational diabetes have had their blood sugar levels drop after using chromium picolinate. The dosage to use varies but many doctors prescribe 1000 mcg every day for victims already suffering from diabetes. Vitamin C has been found to hinder the uptake of chromium. It's, therefore, essential to watch out what you are consuming if you will be taking the supplements. Sustained release chromium will help keep blood levels high with this important mineral and help one manage their blood sugar better.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2802) What Are The Health Benefits Of Inositol Crystals?
Date:
December 28, 2012 10:39 AM
The first isolation of inositol was made by Scherer in the year 1849 who was a renowned Biochemist at the time. Since its discovery, wide spread research has been conducted with successful isolation of inositol and its derivatives in both plants and animals. The physiological functions have been confirmed to differ with respect to the structural form of the inositol, with cis-inositol, myo-inositol, neo-inositol and allo-inositol being some of the inositol's stereoisomers commonly isolated. Our Need for Inositol The human body particularly requires inositol and its derivatives in many physiological processes. It is a major messenger molecule that is used in calcium mediated cell signaling which affects motor function, action of hormones such aldosterone and affects the functioning of some of the neurotransmitters in the brain such as serotonin. Inositol derivatives are also involved in lipid metabolism which helps control the amount of LDP (Bad cholesterol) in the body. Additionally, some of the researches indicate that inositol derivatives are actively involved in suppressing oncogenesis which significantly reduces the risk of suffering from breast and prostate cancers. The human body can produce some of the inositol variants from glucose metabolism but obtaining plant derived inositols is also worthwhile. Food Sources Of Inositol Plant products such as red beans, bran and other cereals contain good levels of inositol although the chelating effect of the inositol by calcium and magnesium ions limits its uptake in the gut. For this reason, use of supplement Crystal Inositols is regarded as the best way to obtain dietary inositol. A majority of the crystal inositols available in the market are chemically combined with other compounds such as Niacin which highly increase their absorption in the intestines. Dissolving these crystals in juices is also highly recommended as it is a better way of taking the supplements since a wide range of other drinks especially the ones that contain caffeine affects the uptake of inositol negatively.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2785) Green Tea - A Powerful Antioxidant
Date:
December 27, 2012 11:45 AM
Green Tea
Green tea which is basically obtained from the leaves of Camellia Sinensis, is treated as a medicinal herb. It is gaining popularity all over the world with its medicinal value, which is used to prevent many diseases. Advantages of Green tea: Consuming green tea on daily basis makes your bones stronger. This is because of the fluoride content present in it, which is very helpful in strengthening the bones.
Why is green tea a powerful antioxidant herb? This herb is considered as powerful antioxidant herb because it EGCG content which helps the body kill free radicals which are harmful and which causes early aging of skin, liver transplantation failure, causes cancer, etc. Green tea contains very high concentration of antioxidants called polyphenols. It is beneficiary to take 2-3 cups of green tea or 2 - 3 - 500mg tablets every day. With regular exercise and proper diet, green tea helps in weight reduction. Regular intake of green tea helps you to be healthy and prevents from attack of diseases. The anti oxidants, which are helpful in defending your body against diseases, are available in high concentration in green tea. It is advised to have at least a cup of green tea every morning on empty stomach.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2779) How Does Prickly Pear Leaf Help with Blood Sugar Control?
Date:
August 02, 2011 02:02 PM
Also known as nopales in its place of origin, all plant species referred to as prickly pear belong to the genus Opuntia. This genus comprises more than 200 species, but only a few are noted for their culinary uses. In Mexico and most of Latin America, it is consumed as a vegetable in general. The juice extracted from the prickly pear leaf is utilized in different niches of many industries. In food and drug industries, it is highly valued for its alkaloids and polyphenols that exhibit bioactive properties. Many health problems recorded in the past few decades have been linked to uncontrolled blood sugar levels. Complex carbohydrates present in the human diet are broken down into simple sugars. In particular, glucose refers to the sugar that enters the systemic circulation. Glucose takes on a central role at the cellular level. It fuels the physiological functions of all cells and tissues, including the brain and the heart. That being said, diets high in simple sugars have been tied to elevated blood sugar. Researchers and medical professionals have noted several factors that lead to metabolic disorders. Genetic abnormalities are something we don’t have control of. On the other hand, lifestyle factors are quite the opposite. It has been reported that sedentary lifestyle and food choices play a major part in the development of illnesses related to glucose metabolism. Experts are convinced that some foods are detrimental to health, but there are sources of nutrition that help maintain healthy glucose levels. Prickly pear leaf belongs to the group of foods that are good for blood sugar. Glycemic index measures how carbohydrates present in our diet influence blood sugar concentration. Simple sugars are always considered unhealthy forms of carbohydrates in that all of them possess a high glycemic index, which means glucose is released into the bloodstream at a very rapid rate. Foods that are easily digested to simple sugars, such as white bread and sweetened beverages, affect blood sugar in the same manner. Organic compounds that occur naturally in prickly pear leaf have a twofold effect. First, it helps lower the glycemic index of carbohydrates in our diet, and thus promotes a gradual release of glucose into the bloodstream. Second, it improves the hormone activity of insulin and fights its functional decline that results in insulin resistance, a common medical condition that precedes type 2 diabetes mellitus. Grab some prickly pear leaf and take control of your life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2384) Why Are Fresh Sprouts Like Alfalfa, Barley, and Wheat So Good for Your Health?
Date:
May 24, 2011 11:22 AM
Sprouts For A Healthier Body!
Fresh sprouts are among the healthiest of all foods. They are You might have heard of the nutritional value of grasses and legumes. Wheatgrass is becoming increasingly popular nowadays as they have been receiving a lot of good press lately. Wheatgrass and barley grass has in fact earned the moniker superfoods. Alfalfa, on the other hand, is a legume recently rediscovered for its phytochemical content. It has been a forage crop for centuries, but human consumptions have steadily increased in the past few years. Apart from the fact that wheat, barley, alfalfa can be consumed as fresh sprouts, they also bring similar benefits to human health. Restore Normal pH Levels Proponents of the alkaline diet believe that the body is in a constant cycle of alkalinity and acidity, which is partially dependent on the foods that we eat. The body raises alkalinity with every acidic by-products of digestion to maintain pH balance. That being said, a significant fraction of the human diet is acid-forming, tipping the balance in the process. Fresh sprouts are often linked to the alkaline diet, which aims to restore pH balance of the body. Have High Nutrient Content Alfalfa, barley grass, and wheatgrass are very good sources of vitamins and minerals. They are particularly rich in dietary minerals that help the body function at its best. Plus, they contain amino acids, essential fatty acids, dietary fiber, and carbohydrates in amounts adequate to complement any other foods that make up a healthy diet. One of the very noticeable improvements after months of consuming fresh sprouts is the increase in red blood cell count. Cleanse the Body of Toxins Aside from the fact that fresh sprouts are effective free radical scavengers, they also improve the natural antioxidant defense of the human body. Wheat, barley, and alfalfa are reliable sources of potassium, magnesium, manganese, and selenium, all of which are involved in chemical reactions that lead to effective removal of toxic by-products of metabolism. Fresh sprouts are capable of neutralizing reactive oxygen species such as free radicals. Furthermore, they facilitate the excretion of toxins. Promote Heart Health
Have you had your sprouts today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2304) What is Myrrh and How Does it Boost My Health
Date:
April 25, 2011 04:22 PM
Myrrh And Your HealthMyrrh is one of the oldest herbal remedies in the East and the West. It had a strong presence in many religious traditions of the ancient world. It was even compared to gold in value at some time in history. Early physicians noted its antibacterial properties and added it to poultices and health tonics. Modern medicine has started to look into its medicinal potential in lowering cholesterol and blood sugar. Inhibits Pain Chemicals Myrrh is obtained from the plant species Commiphora myrrha, though there are other related species that produce the same resinous gum. It is native to the Levant and the surrounding regions. As its use were quite common during the ancient times, it spread to eastern countries, eventually reaching India and China, where it remains an important part of folk medicine practices to this day. In addition to its pleasant aroma, myrrh was prized for its antiseptic and analgesic properties in the old days. It was one of the ingredients used by ancient Egyptians in the mummification of their dead. Throughout the centuries, myrrh has been used primarily as a perfume or wound salve. It has a soothing effect on lesions of body surfaces that seem to remove the perception of pain. Improves Insulin Resistance Earlier studies have noted the benefits of myrrh to patients suffering from diabetes, drawing on its uses in Ayurvedic and Unani medicine. In India, physicians that practice both conventional and Ayurvedic medicine have ascribed certain species of myrrh with properties that remove disorders of the circulatory system, notably high blood sugar. Myrrh decoctions are the usual herbal preparations, but it is also available as liniments, balms, salves, tinctures, and incense. In one laboratory study, myrrh extracts appear to lower serum glucose levels. It is postulated that it ameliorates symptoms of metabolic syndrome by enhancing the effects of the hormone insulin. It increases the sensitivity of cells to insulin, even promoting faster glucose metabolism. In the Middle East, it is one of the mainstays of treatment for diabetes type 2. Reduces Total Lipid Levels Myrrh has been the subject of decades-long research on its role in the management of cholesterol. In the latter half of the 20th century, it was discovered that low-density lipoproteins play a major role in many cardiovascular diseases, such as atherosclerosis. The dichotomy of bad and good cholesterol hit the mainstream media to promote awareness of the lifestyle factors tied to cardiovascular diseases. High-density lipoproteins are dubbed good cholesterol in contrast to low-density lipoproteins, or bad cholesterol. Low-density lipoproteins are actually involved in the formation of plaques within the blood vessel walls that leads to many complications. It has been observed that myrrh reduces total lipid levels in the blood by raising high-density lipoproteins and lowering low-density lipoproteins. Give myrrh a try and experience its health beneficial properties for yourself!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2281) What is Vinpocetine and How Does it Help with Memory?
Date:
March 24, 2011 02:18 PM
Vinpocetine And Brain HealthVinpocetine is a derivative of an organic compound found in the plant species Vinca minor, or common periwinkle. It is best known for its neuroprotective effects and used in Europe and Japan in treatment of age-related cognitive decline. More often than not, its activities inside the human body are described as vasodilator, which means it increases blood flow. It has also seen a growing presence in the North American market as a dietary supplement. Vinpocetine is available as a prescription drug in certain European countries and Japan and has shown to be speed up prognosis of patients who suffered cerebrovascular accident, or CVA, which is commonly referred to as stroke. Most cases of cerebrovascular accident are brought on by ischemia, or very poor circulation of blood to certain parts of the brain. This is exactly what vinpocetine is beneficial for, and recommended dosages have so far yielded very encouraging results. Improves Blood Circulation in the Brain It has long been postulated that one of the mechanisms of action of vinpocetine is limiting the effects of Na+ channels that are sensitive to voltage. This creates a neuroprotective effect believed to contribute to mental clarity and sustained attention. Striatal nerve endings produce extracellular Ca+ ions that induce neuronal damage through a phenomenon called excitotocity. High levels of Ca+ ions are now alleged to be correlated with voltage-sensitive Na+ channels. Striatal nerve endings see a decline in Ca+ ions when Na+ channels are influenced by vinpocetine, and in the process lessen excitotoxicity. Attenuates Ischemic Neuronal Damage In addition to limiting neuronal damage induced by excitotoxicity, which in turn results from cerebral ischemia, vinpocetine plays an active role in the upkeep of brain cells after being subjected to ischemic damage. As a vasodilator, it not only counters the effects of ischemia but also significantly increases the brain’s access to bioactive molecules like oxygen and other nutrients exclusively distributed by the circulatory system. It also inhibits the enzyme phosphodiesterase, which is specialized for the breakdown of cyclic adenosine monophosphate, or cAMP, and cyclic guanosine monophosphate, or cGMP. By so doing, vinpocetine contributes to glucose metabolism and energy production in the brain, and at the same time, improves the distribution of bioactive compounds in the central nervous system. Displays Neuroprotective Activities Vinpocetine and its precursor belong to a group of indole alkaloids known as tryptomines, which are present in the human brain and the rest of the central nervous system in minute quantities. These organic compounds make up several psychoactive drugs and in the human body act as neuromodulators and neurotransmitters in the form of melatonin and serotonin. Vinpocetine in particular displays activities that are primarily anti-inflammatory in nature. Several studies point to its effects on the enzyme complex called IkB kinase, which regulates cellular responses to inflammation, by preventing the translocation of a protein complex called responsible for the process of inflammation within cells. In a Nutshell, vinpocetine can help you think clearer and protect the brain from inflammation and free radical damage. Give vinpocetine a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2257) Natural Remedies To Control Blood Sugar
Date:
June 17, 2010 01:32 PM
Diabetes has now been found to be the seventh leading cause of death in the United States and Canada. It is a chronic disorder of carbohydrate, fat, and protein metabolism. The disease starts off as a variety of metabolic changes that are associated with hyperinsulinemenia and hyperglycemia. When this happens, Insulin Resistance Syndrome results, which is a precursor to actual, full-blown, diabetes. If left untreated, insulin resistance will develop into full-blown diabetes, which includes greatly magnified risks of heart disease, stroke, eye and kidney disease, and loss of nerve function. It should be noted that diabetes is the principal cause of adult blindness and limb amputation. Type 2 diabetes is the most common form of diabetes. In this type of diabetes, the body either does not produce enough insulin or the cells ignore the insulin. Insulin is crucial for the body to be able to use glucose for energy. The body breaks down all of the sugars and starches that you consume into glucose, while insulin takes the glucose from the blood into the cells. When glucose builds up in the blood instead of going into the cells, the cells may be starved for energy immediately, and high blood sugar glucose levels over time can cause damage to your eyes, kidneys, nerves, and heart. Diabetes occurs in people of all ages and races, with some groups having a higher risk for developing it than others. Diabetes is more common in African Americans, Latinos, Native Americans, and Asian Americans, as well as the older aged population. Non-insulin-dependent diabetes, also known as type 2 diabetes, is a disease that is strongly associated with a sedentary lifestyle and the modern western diet. Inadequate physical activity, along with a diet that is high in refined sugars, saturated fats, and proteins, and simultaneously low in dietary fiber has resulted in an obesity epidemic throughout the United States and Canada. With this epidemic has risen the prevalence of type 2 diabetes. In fact, obesity is a main factor in type 2 diabetes, with almost 90% of those diagnosed with type 2 diabetes being obese at the time of diagnosis. Although there is still a disagreement as to whether obesity actually causes type 2 diabetes or whether diabetes causes obesity, there is one thing that is clear: the disease involves a huge disturbance to the metabolic balance of the body and weight is a major factor in blood sugar management. This disturbance leads to dramatic consequences for the individual. In order to reduce the risk of type 2 diabetes, it is crucial that one prevents the onset of insulin resistance. Unfortunately, millions of North Americans unknowingly suffer from this syndrome. This places them at an increased risk for cardiovascular and neurological dysfunctions. Research has shown that complications that are associated with the development of insulin resistance may be mitigated effectively by conscientious dietary and lifestyle changes along with weight loss. Vitamins B3, B6, B12, C, E, biotin, coenzyme Q10, and the trace elements chromium, magnesium, manganese, and zinc are all crucial for proper blood sugar defense and metabolic support, as well as the regulation of glucose metabolism. Supplementation with these nutrients at levels that are determined to be suitable for optimal nutritional health by cited nutritional authorities is an important part of product-rating criteria. Nutritional experts ask themselves whether the product in question contains vitamin B3, vitamin B6, vitamin B12, vitamin C, vitamin E, biotin, coenzyme Q10, chromium, magnesium, manganese, and zinc at potencies that are up to 100% of the potencies for these nutrients in the Blended Standard. Excess weight seems to be a key factor in type 2 diabetes so it seems to reason that reducing body fat can help one improve insulin sensitivity. Losing weight is no easy task but is possible with consistent work. Fortunately, heath food stores have vitamin formulas that may help improve insulin sensitivity, but this is no substitute for good clean eating and exercise. For additional information on these supplements, please contact your local health food retailer.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2168) How to deal with Stress and Cortisol...
Date:
August 30, 2006 09:36 AM
Beating the Aging Odds All of us grow older, but aging is a choice. You have it in your power to retain much of the health, vitality and beauty of your youth. It boils down to a simple fact – retard oxidative stress and you’ll retard the aging process. The 70 million people who make up the “boomer” generation and are getting ready for an active retirement welcome this news. Stress and Cortisol The early twentieth century “stress doctor” Hans Selye, M.D. was renowned for his work on the human adaptive response and the effects of stress on aging. He taught that every stress leanves an indelible scar, and the organism pays for its survival after a stressful situation by becoming a little older. That’s because stress raises levels of the adrenal hormone cortisol. It increases internal generation of free radicals, disrupts normal metabolism and leads to aging conditions. Because of this, cortisol has been dubbed the age-accelerating hormone. The more stressful our lifestyle and the level of environmental hazards we are exposed to, the higher cortisol levels will climb in an effort to jump-start our adaptive response. Coupled with a poor diet, this is a recipe for pre-mature aging. At least eleven major aging factors are related to high cortisol levels:
So, there you have it. Now let’s see how to tame cortisol and reduce oxidative stress. Reducing Cortisol and Oxidative Stress Be in the moment – stress reducing techniques such as meditation, prayer, visualization, yoga, chi gong, and listening to inspirational tapes induce calmness and a sense of balance. Eat right for your genes – as we get older, we don’t digest animal protein as efficiently as when younger. Shifting to plant source proteins that are easier to digest and contain the full complement of vitamins and minerals is most desirable. We are accustomed to thinking of dairy, meat, poultry, and fish as “protein.” All vegetables are good sources of protein. Along with legumes, whole grains, and nuts, daily protein needs are easily fulfilled. Meals that combine a variety of tastes from plant foods also require less salt for flavor enhancement and this helps keep hypertension at bay. So, explore just how good meals can be that either do not contain meat or use it as a condiment. If you do need some salt, try substituting table salt with NOW Vitamins Potassium Chloride crystals. Enzymes Increase Digestion Use digestive enzymes such as Optimal Digestive System to insure that you are absorbing all the nutrients in your food. This product has been clinically tested for its digestive effectiveness helping to digest fats, carbs, proteins and even gas producing beans and cruciferous vegetables. Other enzymes, Serrazimes is a systemic enzyme that will help keep lymphatic’s clear of debris, support immune function, and boost your adaptive response to stress. Tame Cortisol As many people reach middle age they have a tendency to gain weight around the navel. High stress amps up levels of cortisol that results in increased girth. Middle body fat is considered a significant risk factor for impaired glucose metabolism and cardiovascular disease. Check your waist to hip ratio by dividing your waist measurement in inches by your hip measurement. If you have a ratio of 0.85 or below, you have lower risk of insulin resistance and cardiovascular disease. This measurement is one of the best indicators of cortisol induced metabolic syndrome and weight gain. Super cortisol support with Relora is an herbal, vitamin and mineral formula that’s designed to fight mid-body fat by taming cortisol. Its key ingredient is Relora which is a blend of the herbal extract of Phellodendron amurense and Magnolia officinalis. A small double blind clinical trial found that pre-menopausal obese women – half of whom took Relora – lost a significant amount of weight. These were women who eat in response to stress. Thus the researchers proposed that Relora appeared to reduce cortisol and perceived stress, resulting in weight loss. Super cortisol support also contains Ashwagandha and Rhodiola, herbs traditionally use for increasing adaptive response and reducing stress. You can read about these herbs and other nutritional products in the book 7-syndrome healing: supplement essentials for mind and body. Written by myself and coauthor Jayson Kroner. This book can be ordered from Now Foods. Additionally, Chinese scientists found that the active components in Relora called honokiol and magnolol delayed gastric emptying, which would make you feel full longer. An additional anti-aging benefit was observed by another group of Chinese scientists. They reported that honokiol is a potent arterial thrombosis inhibitor because it inhibits prostacyclin release; a promoter of platelet adhesion. Platelet stickiness increases stroke risk. Phellodendron and Magnolia have been used in Chinese medicine for centuries. Quell Free Radicals Health and longevity essentially rests on the body balance between free radical load and antioxidant reserves. Toxic exposure depletes some of your antioxidant reserves. Eating a diet rich in antioxidant fruits, vegetables, legumes and grains, helps you rebound. Continued toxic exposure will challenge your antioxidant status and may overwhelm your reserves. VitaBerry Plus+ is a powerful antioxidant formula that contains a range of high ORAC fruits that naturally augment the diet. ORAC stands for oxygen radical absorbance capacity. It is a measure of the ability of a food to quell oxygen free radicals, the most dangerous kind. VitaBerry Plus+ is a product after my own heart. In my book The Anti-Aging Solution, I wrote about how different color foods protect DNA and prevent aging. VitaBerry Plus+ contains the important colors described in my bood. You can order your copy from Now Vitamins. True-E Bio Complex rounds out the antioxidant colors. It contains all eight tocopherols and eight tocotrienols in the natural ratio found in “tan” foods such as whole grains and legumes. It is the only natural vitamin E that is produced from soy that has not been genetically modified. The best anti-aging advice I can pass on is from my friend and food columnist Joan Jackson. “Take Pleasure in Your Life TODAY and Enjoy What You Eat”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1362) Best Sugar Balance Svetol (green coffee extract)
Date:
May 05, 2006 06:30 PM
Ingredients Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids. In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.* Benefits Maintains healthy blood sugar levels when used as a part of the diet* CHLOROGENIC ACIDS Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1 Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3 Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5 It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism. A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6 RESEARCH ON SVETOL® Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results. In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7 Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption. The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.* SAFETY Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7 *This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4. 2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402. 3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7. 4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10. 5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15. 6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1258) Benefits of L-Carnitine
Date:
February 12, 2006 03:24 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1218) Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)
Date:
August 02, 2005 03:52 PM
Benefits Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine.4 Thiamine and its Co-enzyme, TPP Thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically-catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name "thiamine diphosphate." In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as "active acetate." Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle (citric acid cycle). The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called "oxidative decarboxylation," and for this reason, TPP was originally referred to as "cocarboxylase." TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below. Benfotiamine and glucose metabolism Benfotiamine normalizes cellular processes fueled by glucose metabolites. As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the Krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.5 In the presence of elevated glucose levels, the electron transport chain, the final ATP-generating system in the mitochondrion, produces larger than normal amounts of the oxygen free radical "superoxide." This excess superoxide inhibits glyceraldehyde phosphate dehydrogenase (GAPDH), as key enzyme in the conversion of glucose to pyruvic acid, resulting in an excess of intermediate metabolites known as "triosephosphates." Increase triosephophate levels trigger several cellular mechanisms that result in potential damage to vascular tissue. Cells particularly vulnerable to this biochemical dysfunction are found in the retina, kidneys and nerves. Benfotiamine has been shown to block three of these mechanisms: the hexosamine pathway, the diaglycerol-protein kinease C pathway and the formation of Advanced Glycation End-poducts. As discussed below, benfotiamine does this by activating transketolase, a key thiamin-dependent enzyme.6 Benfotiamine stimulates tranketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.* Transketolase diverts the excess fructose-6-phosphate and glyceraldehydes-3-phosphate, (formed by the inhibition of GAPDH, as mentioned above), into production of pentose-5-phosphates and erythrose-4-phosphate and away from the damaging pathways. Benfotiamine activates transketolase activity in bovine aortic endothelial cells incubated in glucose.6 To test benfotiamine’s ability to counteract these metabolic abnormalities caused by elevated blood glucose, studies have been done in diabetic rats. Benfotiamine increases transketolase activity in the retinas of diabetic rats, while concomitantly decreasing hexosamine pathway activity, protein kinase C activity and AGE formation.6 Benfotiamine and Protein glycation Benfotiamine controls formation of Advanced Glycation End-products (AGEs). AGEs have an affinity for proteins such as collagen, the major structural protein in connective tissue. AGEs are formed through abnormal linkages between proteins and glucose. This occurs via a non-enzymatic glycosylation reaction similar to the "browning reaction" that takes place in stored food.7 At high glucose concentrations, glucose attaches to lysine, forming a Schiff base, which in turn forms "early glycosylation products." Once blood glucose levels return to normal levels, the amount of these early glycosylation products decreases, and they are not particularly harmful to most tissue proteins. On long-lived proteins such as collagen, however, early glycosylation products are chemically rearranged into the damaging Advanced Glycation End-products. AGE formation on the collagen in coronary arteries causes increased vascular permeability. This vessel "leakiness" allows for abnormal cross-linking between plasma proteins and other proteins in the vessel wall, comprising vascular function and potentially occluding the vessel lumen. A number of other potentially harmful events may also occur, including production of cytokines that further increase vascular permeability. Endothelin-1, a strong vasoconstrictor, is over produced, increasing the possibility of thrombosis and generation of oxygen free radicals is stimulated.8 It is vitally important to support normal glucose metabolic pathways so that formation of AGEs is minimized. Benfotiamine, in the test tube (in vitro) prevents AGE formation in endothelial cells cultured in high glucose by decreasing the glucose metabolites that produce AGEs.9 Endothelial cells make up the membranes that line the inner walls of organs and blood vessels. In a rat study comparing the effects of Benfotiamine with water-soluble thiamin, Benfotiamine inhibited AGE formation in diabetic rats while completely preventing formation of "glycooxidation products," which are toxic by products of chronic elevated blood glucose. AGE levels were not significantly altered by thiamin.10 Benfotiamine also normalized nerve function in the animals. After three months of administration, "nerve conduction velocity (NCV)," a measure of nerve function, was increased by both benfotiamine and thiamin; at six months, NCV was normalized by benfotiamine, whereas thiamin produced no further increases in this parameter. Dysfunctional glucose metabolic pathways leading to AGE formation occurs in endothelial cells of the kidneys. In a recent animal study, benfotiamine was administered to rats with elevated glucose levels. Benfotiamine increased transketolase activity in the kidney filtration system of these rats, while at the same time shifting triosephophates into the pentose pathway and preventing protein leakage.11 Safety Benfotiamine has an excellent tolerability profile and can be taken for long periods without adverse effects.3,12 The statements in this fact sheet have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1. Bitsch R, Wolf M, Möller J. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab 1991;35(2):292-6. 2. Schreeb KH, Freudenthaler S, Vormfelde SV, et al. Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4):319-20. 3. Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther 1996;34(2):47-50. 4. Frank T, Bitsch R, Maiwald J, Stein G. High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. Eur J Clin Pharmacol. 2000;56(3):251-7. 5. Pike RL, Brown ML. Nutrition, An Integrated Approach, 3rd Ed. New York:MacMillan; 1986:467. 6. Hammes H-P, Du X, Edlestein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic neuropathy. Nat Med 2003;9(3):294-99. 7. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci 1984;81(2):583-7. 8. Brownlee M. The pathological implications of protein glycation. Clin Invest Med 1995;18(4):275-81. 9. Pomero F, Molinar Min A, La Selva M, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol 2001;38(3):135-8. 10. Stracke H, Hammes HP, Werkman D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes 2001;109(6):300-6. 11. Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 2003;52(8):2110-20. 12. Bergfeld R, MatsumaraT, Du X, Brownlee M. Benfotiamin prevents the consequences of hyperglycemia induced mitochondrial overproduction of reactive oxygen specifies and experimental diabetic neuropathy (Abstract) Diabetologia 2001; 44(Suppl1):A39.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=721) THE FDA AND STEVIA
Date:
July 15, 2005 12:45 PM
THE FDA AND STEVIA While stevia in no way qualifies as an “artificial sweetener,” it has been subject to rigorous inquiry and unprecedented restraints. In 1986, FDA officials began to investigate herb companies selling stevia and suddenly banned its sale, calling it “an unapproved food additive.” Then in 1991, the FDA unexpectedly announced that all importation of stevia leaves and products must cease, with the exception of certain liquid extracts which are designed for skin care only. They also issued formal warnings to companies and claimed that the herb was illegal. The FDA was unusually aggressive in its goal to eliminate stevia from American markets, utilizing search and seizure tactics, embargoes and import bans. Speculation as to why the FDA intervened in stevia commerce points to the politics of influential sugar marketers and the artificial-sweetener industry. During the same year, the American Herbal Products Association (AHPA) began their defense of the herb with the goal of convincing the FDA that stevia is completely safe. They gathered documented literature and research on both stevia and other non-caloric sweeteners. The overwhelming consensus was that stevia is indeed safe, and the AHPA petitioned the FDA to exempt stevia from food additive regulations. Food Additive vs. Dietary Supplement FDA regulations of stevia were based on its designation as a food additive. The claim was that scientific study on stevia as a food additive was inadequate. Ironically, extensive Japanese testing of stevia was disregarde—regardless of the fact that this body of documented evidence more than sufficiently supported its safe use. Many experts who have studied stevia and its FDA requirements have commented that the FDA wants far more proof that stevia is safe than they would demand from chemical additives like aspartame. Stevia advocates point out that stevia not a food additive, but rather, a food. Apparently, foods that have traditionally been consumed do not require laborious and expensive testing for safety under FDA regulations. The fact that so many toxicology studies have been conducted in Japan, coupled with the herb’s long history of safe consumption, makes a strong case for stevia being accepted by the FDA as a safe dietary substance. Still, it was denied the official GRAS (generally recognized as safe) status and designated a food additive by the FDA. The FDA Reverses Its Position As a result of the Health Freedom Act passed in September of 1995, stevia leaves, stevia extract, and stevioside can be imported to the United States. However, ingredient labels of products that contain stevia must qualify as dietary supplements. Stevia had been redesignated as a dietary supplement by the FDA and consequently can be legally sold in the United States solely as a supplement. Its addition to teas or other packaged foods is still banned. Moreover, stevia cannot, under any circumstances, be marketed as a sweetener or flavor enhancer. SUGAR, SUGAR EVERYWHERE Ralph Nader once said, “If God meant us to eat sugar, he wouldn’t have invented dentists.” The average American eats over 125 pounds of white sugar every year. It has been estimated that sugar makes up 25 percent of our daily caloric intake, with soda pop supplying the majority of our sugar ingestion. Desserts and sugar-laden snacks continually tempt us, resulting in an escalated taste for sweets. The amount of sugar we consume has a profound effect on both our physical and mental well-being. Sugar is a powerful substance which can have drug-like effects and is considered addictive by some nutritional experts. William Duffy, the author of Sugar Blues, states,“The difference between sugar addiction and narcotic addition is largely one of degree.” In excess, sugar can be toxic. Sufficient amounts of B-vitamins are actually required to metabolize and detoxify sugar in our bodies. When the body experiences a sugar overload, the assimilation of nutrients from other foods can be inhibited. In other words, our bodies were not designed to cope with the enormous quantity of sugar we routinely ingest. Eating too much sugar can generate a type of nutrient malnutrition, not to mention its contribution to obesity, diabetes, hyperactivity, and other disorders. Sugar can also predispose the body to yeast infections, aggravate some types of arthritis and asthma, cause tooth decay, and may even elevate our blood lipid levels. Eating excess sugar can also contribute to amino acid depletion, which has been linked with depression and other mood disorders. To make matters worse, eating too much sugar can actually compromise our immune systems by lowering white blood cells counts. This makes us more susceptible to colds and other infections. Sugar consumption has also been linked to PMS, osteoporosis and coronary heart disease. Why Do We Crave Sweets? Considering the sobering effects of a high sugar diet, why do we eat so much of it? One reason is that sugar gives us a quick infusion of energy. It can also help to raise the level of certain brain neurotransmitters which may temporarily elevate our mood. Sugar cravings stem from a complex mix of physiological and psychological components. Even the most brilliant scientists fail to totally comprehend this intriguing chemical dependence which, for the most part, hurts our overall health. What we do know is that when sugary foods are consumed, the pancreas must secrete insulin, a hormone which serves to bring blood glucose levels down. This allows sugar to enter our cells where it is either burned off or stored. The constant ups and downs of blood sugar levels can become exaggerated in some individuals and cause all kinds of health problems. Have you ever been around someone who is prone to sudden mood swings characterized by violent verbal attacks or irritability? This type of volatile behavior is typical of people who crave sugar, eat it and then experience sugar highs and lows. Erratic mood swings can be linked to dramatic drops in blood sugar levels. Hypoglycemia: Sign of Hard Times? It is rather disturbing to learn that statisticians estimate that almost 20 million Americans suffer from some type of faulty glucose tolerance. Hypoglycemia and diabetes are the two major forms of blood sugar disorders and can deservedly be called modern day plagues. Hypoglycemia is an actual disorder that can cause of number of seemingly unrelated symptoms. More and more studies are pointing to physiological as well as psychological disorders linked to disturbed glucose utilization in brain cells. One study, in particular, showed that depressed people have overall lower glucose metabolism (Slagle, 22). Hypoglycemia occurs when too much insulin is secreted in order to compensate for high blood sugar levels resulting from eating sugary or high carbohydrate foods. To deal with the excess insulin, glucagon, cortisol and adrenalin pour into the system to help raise the blood sugar back to acceptable levels. This can inadvertently result in the secretion of more insulin and the vicious cycle repeats itself. A hypoglycemic reaction can cause mood swings, fatigue, drowsiness, tremors, headaches, dizziness, panic attacks, indigestion, cold sweats, and fainting. When blood sugar drops too low, an overwhelming craving for carbohydrates results. To satisfy the craving and compensate for feelings of weakness and abnormal hunger, sugary foods are once again consumed in excess. Unfortunately, great numbers of people suffer from hypoglycemic symptoms. Ironically, a simple switch from a high sugar diet to one that emphasizes protein can help. In addition, because sugar cravings are so hard to control, a product like stevia can be of enormous value in preventing roller coaster blood sugar levels. One Colorado internist states: People who are chronically stressed and are on a roller coaster of blood sugar going up and down are especially prone to dips in energy at certain times of day. Their adrenals are not functioning optimally, and when they hit a real low point, they want sugar. It usually happens in mid-afternoon when the adrenal glands are at their lowest level of functioning. (Janiger, 71) Our craving for sweets in not intrinsically a bad thing; however, what we reach for to satisfy that craving can dramatically determine how we feel. Stevia can help to satisfy the urge to eat something sweet without changing blood sugar levels in a perfectly natural way and without any of the risks associated with other non-nutritive sweeteners. Diabetes: Pancreas Overload? Diabetes is a disease typical of western cultures and is evidence of the influence that diet has on the human body. Perhaps more than any other disease, diabetes shuts down the mechanisms which permit proper carbohydrate/sugar metabolism. When the pancreas no longer secretes adequate amounts of insulin to metabolize sugar, that sugar continues to circulate in the bloodstream causing all kinds of health problems. The type of diabetes that comes in later years is almost always related to obesity and involves the inability of sugar to enter cells, even when insulin is present. Diabetes can cause blindness, atherosclerosis, kidney disease, the loss of nerve function, recurring infections, and the inability to heal. Heredity plays a profound role in the incidence of diabetes, but a diet high in white sugar and empty carbohydrates unquestionably contributes to the onset of the disease. It is estimated that over five million Americans are currently undergoing medical treatment for diabetes and studies suggest that there are at least four million Americans with undetected forms of adult onset diabetes. Diabetes is the third cause of death in this country and reflects the devastating results of a diet low in fiber and high in simple carbohydrates. Most of us start our children on diets filled with candy, pop, chips, cookies, doughnuts, sugary juice, etc. Studies have found that diabetes is a disease which usually plagues societies that eat highly refined foods. Because we live in a culture that worships sweets, the availability of a safe sweetener like stevia, which does not cause stress on the pancreas is extremely valuable. If sugar consumption was cut in half by using stevia to
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=642) Cinnamon may control sugar levels...
Date:
July 08, 2005 10:48 AM
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=565) Kal - Vanadyl Complex now with Cinnamon Bark for Blood sugar
Date:
July 01, 2005 03:07 PM
Cinnamon May Help Lower Blood Sugar!Kal Vanadyl Complex Vanadyl Complex - Dietary supplement contains Cinnamon Plus a variety of natural ingredients intended to provide nutritive support for normal, healthy blood glucose, and glycogen synthesis. The formula Contains:
100mg Vitamins C (as ascorbic Acid) - a water soluble nutrient that may help support carbohydrate metabolism and healthy blood glucose levels. 50 mcg Chromium (as Chromium Picolinate) - an essential micromineral that may also help provide nutritive support for healthy carbohydrate metabolism. 10mg Vanadyl Sulfate - the salt of the mineral vanadium that may support glucose oxidation and glycogen synthesis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=544) GREEN TEA EXTRACT - For Antioxidant Support
Date:
June 29, 2005 01:16 PM
For centuries the art of drinking and serving tea has played a major cultural role in many Asian countries. Americans are now discovering this healthful brew. Studies have shown that green tea is a powerful antioxidant that supports cardiovascular health and promotes dental health and glucose metabolism. The polyphenols are the most beneficial components in green tea, especially the catechin EGCG. Source Naturals offers two convenient ways to get the benefits of green tea: a highly concentrated, 100 mg GREEN TEA EXTRACT or the higher potency 500 mg GREEN TEA EXTRACT. Both extracts are standardized for polyphenols, particularly EGCG. The Tale of Tea Green, black and oolong teas are all processed from the young leaves of Camellia sinensis, a white-flowered evergreen that originated in southeastern Asia. Monks brought it to Japan and from there it spread around the world. The three basic types of tea are classified by processing method. Black tea is made by fermenting and roasting the leaves, giving it a dark color and rich taste. Oolong is partially fermented. Green tea is lightly steamed so it retains the chlorophyll of the leaf and its green color, along with high concentrations of polyphenol compounds. The Science of Green Tea All teas contain polyphenols, which are chemical compounds that act as antioxidants. In green tea the main polyphenols are the catechins, including gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC), and epigallocatechin gallate (EGCG). Studies have shown that these catechins are the beneficial, health-promoting components of green tea, especially EGCG, a proven powerful antioxidant. Health Benefits Catechins have significant antioxidant power and may prove to be heart healthy agents in combating lipid peroxidation within the cell membranes that line arterial walls. Antioxidants neutralize destructive free radicals and support cardiovascular health by preventing the oxidation of cholesterol. Oxidized cholesterol is an unstable molecule that damages the integrity of arteries. Research shows that EGCG is a much more potent antioxidant than vitamin C or vitamin E. The catechins in green tea have been shown to fight foreign organisms and help prevent the plaque buildup that leads to poor dental health. Research shows that green tea also promotes healthy glucose levels in the blood stream by enhancing the action of insulin. Natural Wellness Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN TEA EXTRACT. There is a wealth of research supporting the benefits of green tea. If drinking it isn’t your cup of tea, try Source Naturals concentrated GREEN TEA EXTRACTS - standardized for polyphenol content. Standardization provides you with the assurance that you are getting a consistent concentration of these compounds in each dose.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=529) GREEN COFFEE EXTRACT - Powerful Natural Antioxidant
Date:
June 29, 2005 11:06 AM
According to the National Coffee Association’s 2001 National Coffee Drinking Trends survey, 52 percent, or 107 million, U.S. adults drink coffee each day. Although you may already enjoy coffee as your favorite way to begin the morning, new studies are revealing its impressive health benefits. GREEN COFFEE EXTRACT (GCA®) is a newly discovered powerful antioxidant that helps protect against oxidative stress caused by free radicals - a major cause of accelerated aging. Source Naturals GREEN COFFEE EXTRACT (GCA®) is a patent-pending, all-natural green coffee bean extract derived from raw, unroasted coffee beans. It is high in chlorogenic and caffeic acids, two primary compounds responsible for its antioxidant activity. GREEN COFFEE EXTRACT is naturally low in caffeine and contains at least 65 percent total polyphenol antioxidants. The Coffee Story The history of coffee dates back more than a thousand years. Originally, coffee beans were used as food. East African tribes would grind the coffee berries together, mixing the results into a paste with animal fat. Later, around 1000 AD, Ethiopians made a type of wine from coffee berries, fermenting the dried beans in water. Coffee also grew naturally on the Arabian Peninsula where it was first developed into a hot drink. Despite decades of research on coffee and caffeine, there are many misconceptions about the potential health risks associated with coffee, while many of the beneficial aspects have gone unnoticed. Polyphenols: Powerful Antioxidants Phenolic compounds, or polyphenols, are a widespread family of compounds found in all plants including grapes, coffee and tea. They possess outstanding antioxidant and free radical scavenging properties, which may help defend cells and protect the body against the effects of aging. The high antioxidant activity observed in research on coffee is believed to be mostly due to the phenolic acids. GREEN COFFEE EXTRACT contains a number of polyphenols called hydroxycinnamic acids, with the two most prominent being chlorogenic and caffeic acids. Caffeic acid is the most abundant phenolic compound in coffee. In vitro and in vivo studies show that these acids protect against low-density lipoprotein (LDL) oxidation and lipid peroxidation. glucose metabolism There is accumulating evidence that certain dietary polyphenols, such as chlorogenic acid, may have biological effects in the small intestine that alter patterns of glucose uptake. Chlorogenic acid has been shown to inhibit glucose 6 phosphate (Glc-6-Pase) activity. Glc-6-Pase is an enzyme that has a key role in regulating glucose metabolism. An in vivo study on rats demonstrated that chlorogenic acid improved glucose tolerance. Natural Wellness Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN COFFEE EXTRACT.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=525) Promilin Fenugreek Extract - Supports Healthy Blood Sugar Levels
Date:
June 28, 2005 10:44 AM
.. Your body’s ability to manage blood sugar may well be the single most crucial factor affecting your health and longevity, and the one most affected by diet and lifestyle. But today’s high-glycemic carbs and sugar-laden foods — combined with lack of exercise — are creating a serious challenge to your body’s intricate glucose/insulin regulatory system. The resulting cellular stress and deterioration have serious repercussions for both your mind and body. To promote optimal wellness through healthy sugar metabolism, Source Naturals formulated PROMILIN™ FENUGREEK EXTRACT, a potent extract from the highly valued herb fenugreek, into an advanced nutritional supplement designed to assist insulin production and support healthy glucose levels. As a complement to your diet, Source Naturals PROMILIN™ FENUGREEK EXTRACT is an excellent strategy to improve blood sugar levels, and consequently, quality of life. The basis of Source Naturals PROMILIN™ FENUGREEK EXTRACT is fenugreek (Trigonella foenum-graecum), a respected culinary and medicinal herb used throughout history. One of the formula’s fenugreek extracts is rich in galactomannan, a mucilaginous fiber that may benefit the bowel. The other extract is Promilin, a patent-pending complex of bioactive amino acids standardized to contain 20% 4-hydroxyisoleucine. This extraordinary amino acid derivative assists the pancreas in production of insulin. Several studies with animals and with human cell cultures demonstrate this extract’s positive effect on reducing post-meal glucose levels — with little or no increase in blood insulin concentrations — a clear indicator of improved insulin sensitivity. Sports Nutrition and Blood Sugar Athletic energy and endurance depend on the ability of muscles to recover from exercise. Because PROMILIN promotes utilization of glucose and insulin by the the body’s muscle cells, “weekend warriors” will feel less fatigue on Monday morning. In a clinical study, PROMILIN increased glycogen re-synthesis by 63% over carbohydrate alone. This is the rate at which post-exercise muscle glycogen (energy) is restored. PROMILIN may also play a role in weight management because it helps your body metabolize carbohydrates more efficiently. And the less time glucose spends in your bloodstream, the less chance it will be converted into fat. By supporting glucose metabolism, Source Naturals PROMILIN™ FENUGREEK EXTRACT may help protect against a harmful process called glycation, where excess glucose reacts with amino acids to form crosslinked sugardamaged proteins that damage the linings of blood vessels, the lens of the eye, and the myelin sheath that insulates brain cells.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=513) REFERENCES
Date:
June 25, 2005 08:13 PM
REFERENCES 1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. 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Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=507) VANADIUM W/CHROMIUM - Supports Healthy Blood Sugar Levels
Date:
June 24, 2005 05:15 PM
Today’s sedentary lifestyles and sugar-rich, nutrient-poor foods are contributing to the rise of obesity in our society. The result: challenges to your body’s system of balancing blood sugar levels and insulin activity. Maintaining a healthy diet and lifestyle helps keep blood sugar levels in the normal range, but sometimes you need nutritional support when you don’t have time to make those healthy food choices. Source Naturals, the science company, introduces VANADIUMW/CHROMIUM for blood sugar support. Research shows that these two important minerals help maintain normal blood sugar levels when used as part of your diet. Vanadium works together with chromium to support healthy blood sugar levels. Research has shown that both of these important minerals play a key role in normal insulin function. Vanadium: Balances Insulin Activity Vanadium, named after Vanadis the Norse goddess of beauty, belongs to a group of biologically important metals known as transition elements. These metals have a natural tendency to form complexes with organic compounds called coordination compounds that serve important biological functions. Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. The sugar that remains in the blood can create problems by binding with protein molecules, resulting in damaged, non-functioning structures, in a process called glycation. Some evidence suggests that vanadium supports these vital metabolic processes because of its ability to mimic the actions of insulin. More Absorbable Form of Vanadium Absorption of dietary vanadium and supplemental vanadium is poor. It is estimated that less than 5% of dietary vanadium is absorbed. Organic forms of vanadium, such as bis-glycinato oxovanadium or BGOV, are recognized as being more absorbable. BGOV is an organically bound, bioavailable form of vanadium complexed with the amino acid glycine. Glycine, an amino acid found in the protein of all life forms, generates superior vanadium absorption. Chromium: Supports glucose metabolism Chromium is a trace element the body needs in very small amounts, but it plays a significant role in human nutrition. Its most important function is to help regulate the amount of glucose in the blood. Insulin plays a role in this process, by regulating the movement of glucose out of the blood and into the cells. Chromium is a key constituent of the compound known as glucose tolerance factor (GTF). This mineral enhances the effectiveness of insulin, encouraging glucose to enter cells, where it can be burned for fuel. Chromium participates in glucose metabolism by enhancing the effects of insulin. Insulin binds to insulin receptors on the surface of cells, activating those receptors and stimulating glucose uptake by cells. Through its interaction with insulin receptors, insulin provides cells with glucose for energy and prevents blood glucose levels from becoming elevated. Glucose buildup in the bloodstream is associated with adverse changes in lipid profiles and increased challenges for cardiovascular health. Some studies examining the effects of chromium supplementation on lipid profiles have observed reduction in serum total cholesterol, LDL cholesterol, and triglyceride levels. Source Naturals VANADIUM W/CHROMIUM includes ChromeMate®, a patented compound of chromium and niacin with proven GTF activity. Wellness Nutrition Taking responsibility for your health is at the heart of the wellness revolution. Sometimes life may seem like it’s passing you by and you may not have time to focus on staying healthy. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you products like VANADIUM W/CHROMIUM to help you maintain a healthy balance. References: Anderson, R.1998. Chromium, glucose intolerance and diabetes. Journal of the American College of Nutrition 17(6):548-555. Jellin, J., et al. 2004. Vanadium Monograph. Pharmacists Letter/Prescribers Letter Natural Medicines Comprehensive Database. Therapeutic Research Facility. Nandhini, S., et al. 1993. Insulin-like effects of bis-glycinato oxovanadium complex on experimental diabetic rats. Indian Journal of Biochemistry and Biophysics 30:73-76.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=420) Enhancer for Youthful Vitality
Date:
June 16, 2005 08:20 PM
NEW PRODUCT ANNOUNCEMENT Enhancer for Youthful Vitality
Five tablets contain: Suggested Use: 5 tablets before exercise and/or at bedtime with plenty of water at least two hours after the last meal. Discontinue use or reduce dosage if any of the following symptoms are present: nausea, excessive salivation, vomiting, diarrhea, muscle spasms, cramps, excessive urination, insomnia, headache, cardiac arrhythmias, high blood pressure, or changes in mood or emotional balance.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=369) The Blood Sugar Blues - help lower blood sugar
Date:
June 12, 2005 08:08 AM
The Blood Sugar Blues by Carl Lowe Energy Times, July 10, 2003 The cells in your body run on the sugar they get from blood. Normally, this energy distribution system functions efficiently. When things go awry, however, blood sugar fluctuations can cause serious problems. If your blood sugar stays too high, your pancreas, heart and other organs suffer. But stabilize your blood sugar and you can stabilize your health. Problems linked to too much blood sugar are widespread. Diabetes, in which the body becomes increasingly unable to regulate blood sugar levels, is one of the most serious and widespread conditions. Plus, researchers now know that elevated blood sugar, even if you don't suffer diabetes, elevates your risk of heart disease and pancreatic cancer (JAMA 5/17/00). Researchers at the Northwestern University Medical School have shown that with every bump up in your blood sugar levels, your chances of contracting pancreatic cancer rises significantly. "Because the prevalence of type 2 (adult onset) diabetes and obesity, including childhood obesity, is steadily increasing, identifying a potential causal association between hyperglycemia (high blood sugar) and pancreatic cancer could have important preventive and prognosticative implications for this cancer," notes Susan M. Gapstur, MD, a professor at Northwestern. In other words, measuring your blood sugar can go a long way towards measuring the odds of developing this devastating condition. In the United States, pancreatic cancer is the fifth most deadly cancer. The disease is difficult to discover, and tumors in the pancreas usually remain hidden until the cancer has spread throughout the body. Blood Sugar and Heart Problems A collection of researchers now believes your blood sugar level so closely predicts your heart disease risk that blood sugar may be a more accurate heart disease predictor than cholesterol. According to a study in England (BMJ 2001; 322:15), the higher your blood sugar level, the higher your risk of heart disease and other serious health problems. In particular, a type of blood sugar called glycated hemoglobin may provide an indication of what kind of trouble your heart and arteries may face in the future. Glycated hemoglobin is blood glucose (sugar) that has latched onto your red blood cells. The levels of this type of attached sugar climbs when blood sugar levels consistently stay too high. After a while, this sugar not only sticks to blood cells, it also starts sticking to other tissues, an occurrence that can lead to cardiovascular disease. While about one in twenty people in their late 40s or older has diabetes, experts estimate that almost three out of four have at least some degree of elevated glycated hemoglobin. Higher and Higher Men and postmenopausal women are at highest risk for elevated blood sugar. Your blood sugar also generally increases:
You can lower your risk of forming glycated hemoglobin by taking the antioxidant vitamins C and E and drinking three or four alcoholic drinks a week (American Journal of Clinical Nutrition 2000: 71(5)). In addition, losing weight and exercising also drops your glycated hemoglobin. Helpful Chromium When glucose enters the bloodstream after a meal, it has a variety of possible destinations. It can be picked up by brain cells, which use glucose as their only source of fuel (this explains why low blood sugar can cause headaches, dizziness and shakiness). Glucose also can enter muscles, which can burn either glucose or fat for energy. Or glucose can enter fat cells for storage-not a desirable option for someone who is already overweight. One reason blood sugar may rise to unhealthy levels is a condition called glucose resistance or intolerance, which occurs when insulin, the hormone-like substance that shepherds glucose into the body's cells, can't do its job efficiently. That leads to blood which is too rich in both sugar and insulin. Researchers believe that the element chromium can help the body use insulin more effectively, which, when combined with adequate exercise, allows glucose to more easily enter muscle cells. "In experiments, chromium supplementation has actually been found to improve glucose tolerance in some diabetics and in people with impaired glucose tolerance," says nutrition researcher and teacher Shari Lieberman, PhD, in The Real Vitamin and Mineral Book (Avery/Penguin). In a number of investigations, chromium has not only helped improve glucose tolerance, but it has also decreased circulating insulin, glycated hemoglobin and cholesterol levels (Journal of the American College of Nutrition 1998; 17:548-55). (People with elevated glucose levels often suffer from elevations in cholesterol as well. In the search for ways to improve cholesterol levels, Germany's Commission E, an herbal authority respected around the world, has approved the use of garlic to help support healthy cholesterol.) Ginseng and Blood Sugar American ginseng, an herb known as an adaptogen (which means it helps the body cope with everyday stress) is another tool for controlling blood sugar. Research at St. Michael's Hospital and the University of Toronto shows that taking American ginseng (Panax quinquefolium) about 40 minutes before you eat can reduce your blood sugar (Archives of Internal Medicine 4/9/00). According to Vladimir Vuksan, MD, lead investigator for the research team, these findings may have important implications for the treatment and prevention of diabetes. "Although preliminary, these findings are encouraging and indicate that American ginseng's potential role in diabetes should be taken seriously and investigated further. Controlling after-meal blood sugar levels is recognized as a very important strategy in managing diabetes. It may also be important in the prevention of diabetes in those who have not yet developed the disease," says Dr. Vuksan. Fat vs Sugar Supplemental helpings of the fatty acid conjugated linoleic acid (CLA) have also been shown to control blood sugar and lower your risk of diabetes (Journal of Nutrition 1/03). "In previous work, we found that CLA delayed the onset of diabetes in rats," says Martha Belury, PhD, the senior author of the investigation and an associate professor of human nutrition at Ohio State University. "In (our latest) study, we found that it also helped improve the management of adult-onset diabetes in humans." Dr. Belury's research shows that CLA may help lower levels of leptin, a hormone believed to regulate fat levels. By reducing leptin, CLA may help reduce body fat, which, in turn, may lower the risk of diabetes and high blood sugar. Sweet Workouts A consistent, long-term exercise program is one of the single best ways to convince your body to temper blood sugar levels and lower your risk of developing diabetes (Clinical Exercise Physiology 2/15/02). "It now appears that there is...a long-term beneficial effect from regular exercise, most likely due to the fact that a significant amount of fat is lost," says exercise physiologist Cris Slentz, PhD. "Long-term exercise leads to loss of fat in the gut (stomach) region, which is especially beneficial since this fat is thought to be directly linked to increased risk of diabetes and heart disease." Dr, Slentz's study examined how exercise influences the way the body uses sugar in people who have a high risk of diabetes. In this research, five overweight individuals who had never exercised before engaged in an intensive workout program for nine months. Afterwards, they went back to their couch potato lives. Dr. Slentz and other investigators measured their blood sugar before they started the exercise program and then remeasured these levels at one day, five days and thirty days after the nine-month regimen ended. The researchers also looked at these people's insulin sensitivity, a measure of how well their bodies controlled blood sugar. "Insulin sensitivity, or its ability to stimulate glucose metabolism, was higher after nine months of exercise, and the fasting insulin levels were lower," Slentz said. "Just as importantly, 30 days after stopping exercise, insulin sensitivity was still 24% higher than pre-exercise levels, indicating that beneficial effects of exercise persisted." In this study, people pedaled exercise bikes, walked on treadmills and climbed stairs. By the end of the research, they were working out about an hour a day. So if you've put off devoting yourself to an exercise program and taking care of your blood sugar, you now have more reason to start as soon as possible. Paying attention to blood sugar pays off.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=301) Battle Fatigue! Don't passively accept chronic exhaustion and weakness.
Date:
June 10, 2005 10:06 PM
Battle Fatigue! Don't passively accept chronic exhaustion and weakness. by Joanne Gallo Energy Times, December 6, 1999 Most folks wouldn't seek the distressing distinction of suffering chronic fatigue syndrome. Aside from a dizzying array of discomforts associated with the malady, the lack of a definitive cause, and few remedies offered by the medical establishment, scornful skeptics lob accusations of laziness or boredom or just plain moodiness. "Snap out of it!" they say, with little sympathy or understanding. "Just get moving!" But if you're one of more than 3 million Americans affected by chronic fatigue, you know your problem is not all in your head. Your symptoms are real and they extend far beyond mere tiredness. In addition to a debilitating sense of fatigue that can make everyday existence feel like an overwhelming struggle, you may suffer from impaired concentration and memory, recurrent sore throats, nagging headaches, muscle and joint pain, swollen lymph nodes and fitful sleep. The persistence of any one of these effects alone could be debilitating, but the overall diminished capabilities of the chronic fatigue sufferer can become the most discouraging aspect of the disease. But before you give up hope on kicking this energy-sucking ailment, look to natural ways to boost your immune system and regain your stamina for a more healthy and productive life. New research points to powerful, energy enhancing supplements which, combined with a nutritious diet and stress reducing techniques, can help you reclaim your body from a swamp of sluggishness. Yuppie Flu? Part of the public's misconceptions about chronic fatigue syndrome (CFS) may stem from vague definitions of exactly what it is and its causes. In the '80s, CFS was often mentioned in the same breath as the Epstein-Barr virus, which garnered much notoriety as the "yuppie flu": a state of chronic exhaustion that often plagued young, overworked professionals, as the media trumpeted. CFS was initially thought to be the result of the Epstein-Barr virus, and the two were often considered to be the same thing. Since the Epstein-Barr virus causes mononucleosis, the term "chronic mono" was also thrown around to refer to long-lasting states of fatigue. Today, CFS is defined as a separate disorder from the Epstein-Barr syndrome. Researchers have found that CFS is not caused exclusively by the Epstein-Barr virus or any other single infectious disease agent. According to the Centers for Disease Control (CDC) in Atlanta, CFS may have multiple causes, in which viruses or other infectious agents might have a contributory role. Some of these additional possible culprits include herpes simplex viruses, candida albicans (yeast organisms), or parasites. According to the CDC, a person can be definitively diagnosed with CFS when she or he experiences severe chronic fatigue for six months or longer that is not caused by other medical conditions, and must have four or more of the following problems recurrently for six consecutive months: tender lymph nodes, muscle pain, multi-joint pain without swelling or redness, substantial impairment in short-term memory or concentration; sore throat, headaches, unrefreshing sleep and postexertional malaise lasting more than 24 hours. Even if you are not diagnosed with CFS, you could still probably use some help in fending off fatigue. You may suffer from another poorly understood condition like fibromyalgia, which causes similar symptoms of exhaustion and pain with additional stomach discomfort. You may cope with another ailment like hypoglycemia or low thyroid function that zaps your energy. Or you could be like almost every stressed-out American adult trying to do it all at the expense of your well-being. Though researchers still search for a definitive cause for CFS, one thing is certain: Constant stress and poor nutritional habits weaken the immune system's ability to ward off a host of debilitating viruses and organisms. So before you run yourself down and succumb to a chronic condition, learn how you can build up your defenses now. Nutrient News Some of the most exciting new research in CFS treatments focuses on NADH or Coenzyme 1, an energy-enhancing nutritional supplement. This naturally-occurring substance is present in all living cells including food, although cooking destroys most of it. Coenzymes help enzymes convert food and water into energy and NADH helps provide cellular fuel for energy production. It also plays a key role in cell regulation and DNA repair, acts as a potent antioxidant, and can reportedly improve mental focus and concentration by stimulating cellular production of the neurotransmitters dopamine, noradrenaline and serotonin. A recent study conducted at Georgetown University Medical Center in Washington, DC, and reported in the February 1999 issue of The Annals of Allergy, Asthma & Immunology, showed that chronic fatigue sufferers improved their condition significantly by taking Enada, the stabilized, absorbable, oral form of NADH. The researchers found that 31% of those who took the supplement achieved significant improvement in relief of their symptoms, and a follow up study showed that 72% achieved positive results over a longer period of time. Coenzyme-A and Coenzyme Q-10 (Co-Q10) are related coenzymes also necessary for energy production. According to Erika Schwartz, M.D., and Carol Colman, authors of Natural Energy: From Tired to Terrific in 10 Days (G.P. Putnam's Sons) CoQ10 in combination with the nutrient carnitine enhances cellular energy production, thereby boosting energy levels. Coenzyme-A is required to initiate the chemical reactions that involve the utilization of CoQ10 and NADH for the production of energy at the cellular level. Another important energy-enhancing nutrient is D-ribose, a simple sugar that is crucial to many processes in your body. D-ribose stimulates the body's production of adenosine triphosphate, or ATP, an energy-rich chemical compound that provides the fuel for all body functions. D-ribose is essential to the manufacture of ATP and maintaining high levels of energy in the heart and skeletal muscles. Vitamin Power In addition to these new nutrients, a host of more familiar vitamins and minerals can help banish fatigue. According to Susan M. Lark, M.D., author of the Chronic Fatigue Self Help Book (Celestial Arts) nutritional supplements help stimulate your immune system, glands and digestive tract, promote proper circulation of blood and oxygen, and provide a calming effect. Some of Lark's recommended nutrients for building and regaining strength include: Vitamin A: Helps protect the body against invasion by viruses that could trigger CFS, as well as bacteria, fungi and allergies. Supports the production and maintenance of healthy skin and mucous membranes, the body's first line of defense against invaders. Also supports the immune system by boosting T-cell activity and contributing to the health of the thymus, the immune-regulating gland. Vitamin B Complex: Depression and fatigue can result from the body's depletion of B vitamins, which can occur from stress or drinking too many caffeinated beverages. Studies have provided preliminary evidence that CFS patients have reduced functional B vitamin status (J R Soc Med 92 [4], Apr. 1999: 183-5). The 11 factors of B complex are crucial to glucose metabolism, stabilization of brain chemistry and inactivation of estrogen, which regulate the body's levels of energy and vitality. n Vitamin C: Helps prevent fatigue linked to infections by stimulating the production of interferon, a chemical that can limit the spread of viruses. Helps fight bacterial and fungal infections by maintaining healthy antibody production and white blood cells. Also necessary for production of adrenal gland hormones which help prevent exhaustion in those under stress. Bioflavonoids: Help guard against fatigue caused by allergic reactions; their anti-inflammatory properties prevent the production of histamine and leukotrienes that promote inflammation. Bioflavonoids like quercetin are powerfully antiviral. Vitamin E: Has a significant immune stimulation effect and, at high levels, can enhance immune antibody response. Zinc: Immune stimulant; improves muscle strength and endurance. Constituent of many enzymes involved in metabolism and digestion. n Magnesium and Malic Acid: Important for the production of ATP, the body's energy source. Magnesium is also important for women who may develop a deficiency from chronic yeast infections. Potassium: Enhances energy and vitality; deficiency leads to fatigue and muscle weakness. Calcium: Combats stress, nervous tension and anxiety. Iodine: Necessary to prevent fatigue caused by low thyroid function, as it is crucial for the production of the thyroid hormone thyroxin. Herbal Helpers In addition to nutrients to bolster your immunity, herbal remedies can also help suppress viral and candida infections. Garlic is a powerful, natural antibiotic, while echinacea and goldenseal have strong anti-infective abilities. Other botanicals help combat tiredness and depression: stimulating herbs such as ginger, ginkgo biloba, licorice root and Siberian ginseng can improve vitality and energy. For anxiety, moodiness and insomnia try passionflower or valerian root, which both have a calming effect on the central nervous system. Eating For Energy Supplements can only do their best if you eat a nutritious diet. Start by cutting out large quantities of sugar, caffeine, alcohol, dairy products, red meat and fat. But what are the best foods when trying to restore energy or recover from illness? "High nutrient content foods with a good balance of proteins and carbohydrates," answers Jennifer Brett, ND, interim clinic director and chair of botanical medicine at the University of Bridgeport College of Naturopathic Medicine. "You want foods with high nutritional value-that's where vegetables end up looking better than fruit." Brett enthusiastically pushes that "universal food," as she calls it: chicken soup. "In China," she says, laughing, "they do make chicken soup, and they do think of it as healing, because they add astragalus and shiitake mushrooms. Vegetable soups with chicken or fish have high nutritional value and are easy to digest." The same principle applies to juices, Brett says. Juices are a good way to tastefully get more phytonutrients from fruits and vegetables into your diet. Toss in protein powder, and you can make a complete meal in your blender. "You get more energy from juicing," she explains, "more accessible nutrients and carbohydrates that are not bound up in fiber." Brett's additional recommendation: oatmeal. "It's got protein and carbohydrates combined with a lot of minerals, which you may not get from a sugary cereal," she says. "Sure, they spray some vitamins on them, but if you don't drink the milk in the bottom of the bowl, you'll miss out on them. You might as well take a multivitamin." Fabulous Fiber Look to fiber for superior energy enhancement. Natural Energy author Schwartz calls it downright "miraculous": "In terms of conserving precious energy, fiber-rich foods are your cells' best friends," she writes. "It takes smaller quantities of them to give you a full, satisfied feeling. They release all their benefits slowly, which allows the cells to extract nutrients with much less effort. Then these fiber-rich foods graciously leave the body with ease and efficiency." Among these "slow burn" foods that Schwartz says raise blood sugar slowly and steadily and maintain energy evenly: Alfalfa sprouts-high in fiber and low in cholesterol. Apples-one medium unpeeled provides 10% of the recommended daily fiber dose; unlike sweeter fruits, which are rich in healthful fiber, they help regulate blood sugar. Broccoli-along with such greens as cauliflower, cabbage, kale, collard greens and broccoli rabe, it's packed with fiber, vitamins and minerals n Brown rice, wild rice, other whole grains-fiber treasure troves, including barley, quinoa, millet and buckwheat. Corn-excellent fiber source. Lentils and other legumes-high in fiber, delicious beans are rich in culinary possibilities. Oat bran and wheat bran-mix into yogurt or add to cereal for the best available access to fiber. Popcorn-an excellent snack. Citrus for More Energy If constant colds and infections are draining your energy, healthy helpings of citrus fruit may be the pickup you need. According to Robert Heinerman, in Heinerman's Encyclopedia of Healing Juices (Parker), citrus fruit have been used for more than a thousand years as natural remedies for a wide variety of ailments: Kumquat juice is supposed to help clear up bronchitis. Lemon juice with a pinch of table salt eases a sore throat. Lime juice in warm water soothes aches and cramps from the flu. Tangerine juice can break up mucous congestion in the lungs. Along with citrus' vitamin C, these fruits also supply carotenoids, antioxidants that provide disease-preventing benefits. Citrus also often contain calcium, potassium, folate (a B vitamin that fights against heart disease), iron and fiber. Fruits are loaded with phytochemicals, naturally occurring chemicals that give fruit their vibrant colors. Yellow, red and orange fruits are also high in flavonoids, like quercetin, a substance which fights cancer. Quercetin also aids in prevention of cataracts and macular degeneration, according to author Stephanie Beling, MD, in her book Power Foods (Harper Collins). Even the US Department of Agriculture agrees on this flavonoid's benefits, noting in its phytochemical database that quercetin is an "antitumor promoter, antiasthmatic, anticarcinogenic, antiplaque, cancer-preventive, capillariprotective." (Quercetin is also available as a supplement.) Don't Avoid Avocados For a vitamin rich food, few items beat the avocado which holds vitamins E and C as well as some B vitamins (B6, niacin, riboflavin). A significant source of beta carotene, though not nearly as much as carrots or sweet potatoes, avocados also contain high amounts of the minerals potassium, magnesium, copper and zinc. Just 15 grams of avocado delivers about 81 international units of vitamin A as beta carotene. Beta carotene, a carotenoid in fruits and vegetables, is converted to vitamin A in the body. This vitamin, aside from providing antioxidant protection from damaging free radicals, is necessary for good eyesight, healthy skin and healing. In addition, the avocado, like all of these healthy foods, tastes great. Which means that you can pep up and not have to sacrifice taste for zest. Healthy Mind, Healthy Body Remember that the path to wellness begins in your mind. Stress-reducing activities like yoga, meditation and massage and aromatherapy can have a great rejuvenating effect on your body. If you can learn to handle stress effectively instead of letting it control you-and strengthen your system with the right nutrients and diet-you'll find that fatigue can be a sporadic visitor rather than a chronic companion.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=284) R-Lipoic Acid - Fulfilling the Potential of Lipoic Acid 
Date:
June 04, 2005 02:23 PM
Lipoic acid may be the body’s most versatile nutrient. Its critical importance for health is scientifically documented. Not only is it a powerful antioxidant, it supports healthy sugar metabolism and liver function, and is integral to energy generation, which affects all biological functions. But few know that the commonly available form, alpha lipoic acid (ALA), is not the same compound that occurs naturally in our bodies. ALA is a 50/50 combination of natural form r-lipoic and synthetic s-lipoic acid—and the synthetic form may actually block the activity of r-lipoic acid, resulting in a weaker product. Because it is the natural form, r-lipoic acid is better absorbed and safely metabolized. And it is up to 10 times more effective at producing cellular energy, according to in vitro research, and may be a more potent antioxidant. Source Naturals, the science company, is proud to be one of the first to offer this breakthrough nutrient: R-LIPOIC ACID R-Lipoic Acid: Key to Cellular Energy Generation Plants capture solar energy in their carbohydrates. In a reverse process called oxidation, animals extract that energy. R-LIPOIC ACID is a vital link in the metabolic pathway that gives us the power to move and the energy of intelligence. R-LIPOIC ACID is synthesized in the mitochondria, the tiny power plants inside every cell that produce energy in the form of ATP. It is safely metabolized and up to 10 times more effective than other forms of lipoic acid in mitochondrial ATP production, according to an in vitro study. Supports glucose metabolism Human and animal studies show that R-LIPOIC ACID can increase glucose uptake by muscle and nerve cells. By enhancing sugar metabolism, R-LIPOIC ACID may protect cells from glycation. In this detrimental process, excess glucose reacts with proteins to create tough crosslinked bonds that damage vital proteins, including the myelin sheath of neurons and the lens of the eye. Scientists believe glycation is a major source of tissue degradation and cellular aging. Collagen, another important protein, is also subject to crosslinking, which inhibits the flexibility of blood vessel walls—one of the most important indicators of cardiovascular health. Increases Antioxidant Protection R-LIPOIC ACID also neutralizes the harmful byproducts of glucose metabolism, free radicals. The body synthesizes barely enough R-LIPOIC ACID for its metabolic needs, and this decreases with age. As mitochondrial energy production becomes less efficient, more free radicals are generated. R-LIPOIC ACID protects cells, particularly in the mitochondria, where most oxygen damage occurs. R-LIPOIC ACID is a leading component of the body’s antioxidant network. Unlike other antioxidants, it is water and fat-soluble, so it neutralizes a greater number and broader range of free radicals, providing more protection. In animal studies, R-LIPOIC ACID slowed the aging process, which may be the result of cumulative oxidative damage. Lipoic acid, known as the “universal antioxidant,” is a strong antioxidant in its own right, but it also directly recycles vitamin C and indirectly recycles vitamin E for continued use. And R-LIPOIC ACID is more efficient than other forms of lipoic acid at increasing levels of the key antioxidants, CoQ10 and glutathione. Commercial alpha-lipoic acid is 50% synthetic s-lipoic acid, which can interfere with natural form R-LIPOIC ACID when both forms compete for binding sites. Tests showed 40% better absorption by R-LIPOIC ACID, as measured by plasma concentration levels. Integral to Your Wellness Program Because it is central to such critical functions as energy generation, antioxidant protection, anti-glycation activity, and liver support, R-LIPOIC ACID belongs at the center of your wellness program. Source Naturals is happy to join forces with your natural foods retailer in bringing you this advanced nutrient.
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Leucine is one of 3 amino acids that increases muscle mass and will also help you to recover after exercise. Leucine supplies the body with energy and regulate blood sugar. Being an essential amino acids, it cannot be synthesized by the body and thus you need to get it from food or supplements. But Can L-Leucine help glucose metabolism and insulin function?
Prickly pear leaf is obtained from a group of cacti known for their positive effect on blood sugar. It is an important source of food and medication for Native Americans since prehistory. It contains unique compounds that display potent antioxidant activity. Studies have shown that its phytochemical content displays potential in the management of 
rich in enzymes that are not found in the human body. These enzymes help facilitate better absorption of vitamins and minerals. Alfalfa, barley, and wheat are examples of plants that are capable of sprouting when soaked in water. They are best consumed fresh when they still contain all of their nutrients. They make excellent ingredients to salads and sandwiches that can complement any meal. They can be processed in juicing machines, too. 
